It is almost 75 years since a British man has won a grand slam singles title with Fred Perry the last man to achieve the feat, in New York in 1936.
Murray has stood on the brink of history twice before, losing to Roger Federer in the final in Melbourne last year and in the US Open final in 2008, and he is conscious of placing too much pressure on himself.
Instead, he will hope to make it third time lucky on a personal level.
"It's more of a personal goal and personal dream of mine," he said.
"So that's what you need to keep in check and not get ahead of yourself.
"The historical thing, it's not something I have thought about that much but it's something that for me personally I want to try to win."
An overwhelming desire to land that elusive title is not always a good thing, however, as Murray pointed out.
"I don't want to get myself so amped up that I play a stinker of a match," he added.
"If you go in thinking 'no-one has won one for 60-odd years and I might never get another chance'...
"I am going to make the most of the opportunity and give 110% but I also need to make sure I am relaxed and calm on the court.
"I don't want to get myself too worked up."
The 23-year-old from Dunblane believes his experience of reaching the final here 12 months ago, where he suffered a comprehensive defeat to Federer, will stand him in good stead this time round.
"It was tough for me but something that I think overall would have made me a better player, stronger mentally," he said.
"They are all experiences that you need to deal with playing at the highest level of sport.
"You lose some tough matches but I hope it will help me tomorrow."
Murray and Djokovic go back a long way and have recently rekindled a friendship which started when they were in their early teens.
Their first encounter was in the southern French city of Tarbes when Murray was 13, a match the Scot claims to have won 6-1 6-0, although he admits: "A lot has changed since then. It will be a bit tougher than that tomorrow."
The pair became close over the next couple of years before they embarked on different paths to the top, Murray heading to Barcelona and Djokovic to Germany and Italy.
"We went different routes," said Murray.
"But I played him the first time when I was about 13.
"We played each other up until we were 15 and then he improved a lot faster than I did. Then I managed to catch up.
"It wasn't really until we got back on the tour that we started playing together a lot and practising together again."
Murray is therefore not expecting too many surprises on the Rod Laver Arena when the match gets under way.
But what he is expecting is a battle.
He said: "It is going to be a tough match. Novak has played a good tournament.
"I think experience-wise we are similar. We are good friends and we practise a lot together.
"There won't be any secrets with our games but it is going to be a brutal match."